Алгоритмы
Пример разработанного ранее алгоритма оценки вероятности совместной детекции двух частиц – independent doublets model (IDM), при всей простоте - превосходящий традиционный из statistical overlap theory (SOT), что показано экспериментально.
► For n components, m observed peaks, there are n-m doublets and ways to choose n-m pairs from all possible pairs.
► The conditional probability to observe m peaks given that n components are present is:
► For a given m, the value of n, that maximizes P(M=m|N=n), is the expected number of components
► The computation-friendly representation of P(M=m|N=n)
► The corresponding algorithm is implemented into the “Peaks and Waves” software.
- Andreyev, D.; Arriaga, E.A. " Prediction of Peak Overlap Frequency Using Independent Doublets Model", Minnesota Chromatography Forum 28th Annual Spring Symposium, Minneapolis, MN, 2007
- Andreyev, D.;"Independent Doublets" model thesis chapter V Development of models and analytical approaches for individual mitochondria Dmitry Stanislavovich Andreyev Ph. D. University of Minnesota Major: Chemistry 2007
